The Connection Between CBD and Gut Health
The Endocannabinoid System and Gut Health
The endocannabinoid system (ECS) is a complex signaling system that plays a role in regulating various bodily functions, including mood, appetite, and pain perception. The ECS is also involved in regulating gut health, including inflammation, motility, and permeability.
Research suggests that the ECS may be modulated by CBD. For example, a study published in the Journal of Neuroinflammation found that CBD Gummies reduced inflammation and oxidative stress in a mouse model of inflammatory bowel disease (IBD). Another study published in the journal Pain found that CBD reduced visceral hypersensitivity, a common symptom of irritable bowel syndrome (IBS), in rats.
CBD and Inflammation
Inflammation is a common underlying factor in many gastrointestinal disorders, including IBD, IBS, and celiac disease. CBD has been shown to have anti-inflammatory properties, which may make it useful for managing these conditions.
For example, a study published in the European Journal of Pain found that CBD reduced inflammation and pain in a mouse model of arthritis. Another study published in the Journal of Crohn’s and Colitis found that CBD reduced inflammation and improved gut function in a mouse model of IBD.
CBD and Gut Motility
Gut motility refers to the movement of food through the digestive tract. Disorders of gut motility, such as gastroparesis and constipation, can lead to digestive symptoms such as bloating, nausea, and abdominal pain.
Research suggests that CBD may have a positive effect on gut motility. A study published in the journal Neurogastroenterology and Motility found that CBD increased gut motility in a mouse model of constipation. Another study published in the Journal of Gastroenterology and Hepatology found that CBD reduced gastroparesis symptoms in a small group of patients with diabetes.
CBD and Gut Permeability
Gut permeability, also known as “leaky gut,” occurs when the lining of the gut becomes more porous than it should be, allowing harmful substances to enter the bloodstream. This can lead to inflammation and other health problems.
Research suggests that CBD may help reduce gut permeability. A study published in the journal Clinical Hemorheology and Microcirculation found that CBD reduced intestinal permeability in a mouse model of acute lung injury.